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Rabbit Anti-GPR12  /PE-Cy3 Conjugated antibody
Rabbit Anti-GPR12 /PE-Cy3 Conjugated antibody
FLJ18149; FLJ97704; G protein coupled receptor 12; G-protein coupled receptor 12; GPCR12; GPCR21; GPR 12; GPR12_HUMAN; MGC138349; MGC138351; Probable G protein coupled receptor GPR12; GPCR 12.
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  • NO.:SL15358R-PE-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Details

Product Name Anti-GPR12 /PE-Cy3
Chinese Name PE-Cy3标记的G protein-coupled receptorGPR12蛋白抗体
Alias FLJ18149; FLJ97704; G protein coupled receptor 12; G-protein coupled receptor 12; GPCR12; GPCR21; GPR 12; GPR12_HUMAN; MGC138349; MGC138351; Probable G protein coupled receptor GPR12; GPCR 12.  
Research Area Cell biology  immunology  Signal transduction  G protein-coupled receptor  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 37kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GPR12 protein
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
GPR12 is a 334 amino acid peptide that is expressed primarily in brain, particularly in regions where neuronal differentiation takes place. GPR12 is coupled to an inhibitory G protein. It positively influences differentiation and maturation of post-mitotic neurons, and it may promote the growth of neuronal precursor cells.

Function:
Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.

Subcellular Location:
Cell membrane; Multi-pass membrane protein (Probable).

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2835 Human

Entrez Gene: 14738 Mouse

Entrez Gene: 80840 Rat

Omim: 600752 Human

SwissProt: P47775 Human

SwissProt: P35412 Mouse

SwissProt: P30951 Rat

Unigene: 123034 Human

Unigene: 153539 Mouse

Unigene: 88417 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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