Product Name	Anti-C9orf115/PE-Cy3
Chinese Name	PE-Cy3标记的9号染色体开放阅读框115抗体
Alias	MGC51999; Peptidyl tRNA hydrolase 1 homolog; PTH; PTH1; PTRH1 peptidyl tRNA hydrolase 1 homolog (S. cerevisiae);PTH_HUMAN.
Research Area	Cell biology  immunology  Chromatin and nuclear signals  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Pig, Cow, Horse, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	23kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human C9orf115
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: PTRH1 is a 214 amino acid protein that belongs to the PTH family. The PTRH1 protein is believed to be involved in RNA splicing, silencing and metabolism. The PTRH1 gene is conserved in chimpanzee, dog, cow, mouse, rat, zebrafish, A.thaliana and rice, and maps to human chromosome 9q34.11. Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. Similarity: Belongs to the PTH family. Database links: Entrez Gene: 138428 Human SwissProt: Q86Y79 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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