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Rabbit Anti-GFPT2/PE-Cy3 Conjugated antibody
Rabbit Anti-GFPT2/PE-Cy3 Conjugated antibody
D fructose 6 phosphate amidotransferase 2; GFAT 2; GFAT2; Glucosamine fructose 6 phosphate aminotransferase [isomerizing] 2; glutamine fructose 6 phosphate transaminase 2; Glutamine:fructose 6 phosphate amidotransferase 2; Hexosephosphate aminotransferase
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  • NO.:SL13342R-PE-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-GFPT2/PE-Cy3
Chinese Name PE-Cy3标记的D-果糖6磷酸转移酶2抗体
Alias D fructose 6 phosphate amidotransferase 2; GFAT 2; GFAT2; Glucosamine fructose 6 phosphate aminotransferase [isomerizing] 2; glutamine fructose 6 phosphate transaminase 2; Glutamine:fructose 6 phosphate amidotransferase 2; Hexosephosphate aminotransferase 2; GFPT2_HUMAN.  
Research Area Cardiovascular  Cell biology  Signal transduction  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 77kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GFPT2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
GFPT2 (glutamine-fructose-6-phosphate transaminase 2), also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis. Expressed in spinal cord, heart and placenta, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for N- and O-linked protein glycosylation. Containing one glutamine amidotransferase type-2 domain and two SIS domains. GFAT2 is encoded by a gene that maps to human chromosome 5q35.3. GFAT2 gene variants have been linked to type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels.

Function:
GFPT2, also known as glutamine fructose 6 phosphate transaminase 2, controls the flux of glucose into the hexosamine pathway. It is probably involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.

Tissue Specificity:
Highest levels of expression in heart, placenta, and spinal cord.

Similarity:
Contains 1 glutamine amidotransferase type-2 domain.
Contains 2 SIS domains.

Database links:

Entrez Gene: 9945 Human

Entrez Gene: 14584 Mouse

Entrez Gene: 360518 Rat

Omim: 603865 Human

SwissProt: O94808 Human

SwissProt: Q9Z2Z9 Mouse

SwissProt: Q4KMC4 Rat

Unigene: 696497 Human

Unigene: 24402 Mouse

Unigene: 16089 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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