Product Name	Anti-DMWD/PE-Cy3
Chinese Name	PE-Cy3标记的强直性肌营养不良相关蛋白9抗体
Alias	dystrophia myotonica containing WD repeat motif; D19S593E; DM 9; DM9; DMR N9; DMR N9 protein; DMRN 9; DMRN9; DMWD; DMWD_HUMAN; Dystrophia myotonica containing WD repeat motif; Dystrophia myotonica containing WD repeat motif protein; Dystrophia myotonica WD repeat containing protein; Dystrophia myotonica WD repeat-containing protein; Dystrophia myotonica-containing WD repeat motif protein; Gene59; Protein 59; Protein DMR-N9.
Research Area	Cell biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DMWD/DMRN9
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3. Function: Could have a regulatory function in meiosis. Subcellular Location: Contains 5 WD repeats. Tissue Specificity: Strongest expression in brain, liver, and testis. Also expressed in kidney and spleen. Similarity: Contains 5 WD repeats. Database links: Entrez Gene: 1762 Human Omim: 609857 Human SwissProt: Q09019 Human Unigene: 515474 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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