Product Name	Anti-Dopamine beta Hydroxylase/PE-Cy3
Chinese Name	PE-Cy3标记的多巴胺β羟化酶抗体
Alias	DBH; DBM; Dopamine beta hydroxylase; Dopamine-Beta-Hydroxylase; Dopamine beta monooxygenase; DOPO_RAT; DOPO_HUMAN.
Research Area	Tumour  Neurobiology  Synthesis and Degradation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DBH
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Dopamine-beta-Hydroxylase (DBH), Dopamine can be transformed into Noradrenalin. Conversion of dopamine to noradrenaline. [SUBUNIT] Homotetramer composed of two non-covalently bound disulfide-linked dimers. [SUBCELLULAR LOCATION] Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (Potential). Belongs to the copper type II ascorbate-dependent monooxygenase family. Function: Conversion of dopamine to noradrenaline. Subunit: Homotetramer composed of two non-covalently bound disulfide-linked dimers (By similarity). Subcellular Location: Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen (By similarity). Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (By similarity). Tissue Specificity: Chromaffin granules of the adrenal medulla and synaptic vesicles of the sympathetic nervous system. Similarity: Belongs to the copper type II ascorbate-dependent monooxygenase family. Contains 1 DOMON domain. Database links: Entrez Gene: 280758 Cow Entrez Gene: 1621 Human Entrez Gene: 13166 Mouse Entrez Gene: 25699 Rat Omim: 223360 Human Omim: 609312 Human SwissProt: P15101 Cow SwissProt: P09172 Human SwissProt: Q64237 Mouse SwissProt: Q05754 Rat Unigene: 223858 Human Unigene: 591890 Human Unigene: 167781 Mouse Unigene: 87166 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Dopamine-β-Hydroxylase（DBH）—多巴胺β羟化酶。可以将多巴胺转化成去甲肾上腺素。是肾上腺素能神经元的标志。

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