Product Name	Anti-NKG2C/PE-Cy3
Chinese Name	PE-Cy3标记的NK细胞受体2C抗体
Alias	Natural killer cell group 2C; natural killer cell protein group 2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NK cell receptor C; CD159 antigen-like family member C; CD159c; KLRC2 protein; NKG2C_HUMAN.
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	Flow-Cyt=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	26kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NKG2C
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells. Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with CD94. Interacts with TYROBP. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 3822 Human Omim: 602891 Human SwissProt: Q9GME8 Chimpanzee SwissProt: P26717 Human SwissProt: Q9MZK6 Rhesus monkey Unigene: 591157 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Natural killer cells活化性受体2C

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