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Rabbit Anti-IL17E/PE-Cy3 Conjugated antibody
Rabbit Anti-IL17E/PE-Cy3 Conjugated antibody
IL-25; Interleukin-17E; IL 17E; IL-17E; IL 25; IL25; Interleukin 17E; Interleukin 25; Interleukin17E; Interleukin25; IL25_HUMAN; interleukin-25 isoform 1 precursor; interleukin-25.
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  • NO.:SL2613R-PE-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    concentration:1mg/ml
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Details

Product Name Anti-IL17E/PE-Cy3
Chinese Name PE-Cy3标记的白介素-17E/白介素25抗体
Alias IL-25; Interleukin-17E; IL 17E; IL-17E; IL 25; IL25; Interleukin 17E; Interleukin 25; Interleukin17E; Interleukin25; IL25_HUMAN; interleukin-25 isoform 1 precursor; interleukin-25.  
Research Area immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 17kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human IL-17E
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Function:
Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.

Similarity:
Belongs to the IL-17 family.

Database links:

Entrez Gene: 64806 Human

Entrez Gene: 140806 Mouse

Omim: 605658 Human

SwissProt: Q9H293 Human

Unigene: 302036 Human

Unigene: 90154 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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