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Product Name Anti-NUP54/PE-Cy3 Chinese Name PE-Cy3标记的NUP54抗体 Alias 54 kDa nucleoporin; MGC13407; Nucleoporin p54; NUP54_HUMAN. Research Area Tumour Cell biology immunology transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 55kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NUP54 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
NUP54 contains FG repeats and it belongs to the NUP54 family. It is a component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Function:
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane
Subunit:
Component of the p62 complex, a complex composed of NUP62, NUP54, and the isoform p58 and isoform p45 of NUPL1
Subcellular Location:
Nucleus, nuclear pore complex (By similarity). Nucleus membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By similarity). Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter
Post-translational modifications:
O-glycosylated
Similarity:
Belongs to the NUP54 family.
Database links:Entrez Gene: 53371 Human
Entrez Gene: 269113 Mouse
Omim: 607607 Human
SwissProt: Q7Z3B4 Human
SwissProt: Q8BTS4 Mouse
Unigene: 430435 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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