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Rabbit Anti-MRPL24/HRP Conjugated antibody
Rabbit Anti-MRPL24/HRP Conjugated antibody
39S ribosomal protein L24, mitochondrial; FLJ20917; MGC22737; MGC9831; Mitochondrial ribosomal protein L24; MRP L18; MRP L24; MRPL 24; OTTHUMP00000038724; OTTHUMP00000038725; OTTHUMP00000038728.
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  • NO.:SL17783R-HRP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC
    concentration:1mg/ml
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Product Name Anti-MRPL24/HRP
Chinese Name 辣根过氧化物酶标记的Mitochondrion核糖体蛋白L24抗体
Alias 39S ribosomal protein L24, mitochondrial; FLJ20917; MGC22737; MGC9831; Mitochondrial ribosomal protein L24; MRP L18; MRP L24; MRPL 24; OTTHUMP00000038724; OTTHUMP00000038725; OTTHUMP00000038728.  
Research Area Cell biology  transcriptional regulatory factor  Cell type markers  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 24kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MRPL24
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

Function:
MRPL24 is a mitochondrial ribosomal protein (MRP). Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. This is a 39S subunit protein.

Subcellular Location:
Mitochondrial

Similarity:
Belongs to the ribosomal protein L24P family; Contains 1 KOW domain.

Database links:

Entrez Gene: 79590 Human

Entrez Gene: 67707 Mouse

Entrez Gene: 295224 Rat

Omim: 611836 Human

SwissProt: Q96A35 Human

SwissProt: Q9CQ06 Mouse

SwissProt: Q66H47 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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