Product Name	Anti-HRC/HRP
Chinese Name	辣根过氧化物酶标记的HRC蛋白抗体
Alias	HCP; HRC; HRC histidine rich calcium binding protein; MGC133236; Sarcoplasmic reticulum histidine-rich calcium-binding protein; SRCH_HUMAN.
Research Area	Cell biology  immunology  Binding protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	77kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HRC
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: HRC is a 699 amino acid that binds low-density lipoprotein with high affinity. As a high capacity calcium binding protein, HRC regulates the sequestration and release of calcium in the lumen of the junctional sarcoplasmic reticulum (SR) of cardiac, skeletal and smooth muscle. This mechanism may involve direct interaction between HRC and the cytoplasmic domain of Triadin, an integral membrane protein of the SR. The gene encoding HRC maps to human chromosome 19q13.33 and mouse chromosome 7 B4 Function: May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. Subcellular Location: Sarcoplasmic reticulum lumen. Similarity: To rabbit HRC. Database links: Entrez Gene: 3270 Human Omim: 142705 Human SwissProt: P23327 Human Unigene: 436885 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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