Product Name	Anti-SFRS5/HRP
Chinese Name	辣根过氧化物酶标记的丝氨酸/苏氨酸SRP40抗体
Alias	Delayed early protein HRS; HRS; Pre mRNA splicing factor SRP40; SFRS 5; Splicing factor arginine/serine rich 5; SRP 40; SRP40.
Research Area	Cell biology  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, )
Applications	ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	31kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SFRS5
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2010] Function: SFRS5 plays a role in constitutive splicing and can modulate the selection of alternative splice sites. It is found in a pre-mRNA splicing complex with SFRS4, SNRP70, SNRPA1, SRRM1 and SRRM2. There are four isoforms. Subcellular Location: Nuclear Database links: Entrez Gene: 6430 Human Omim: 600914 Human SwissProt: Q13243 Human Unigene: 706773 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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