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Product Name Anti-KRT85/HRP Chinese Name 辣根过氧化物酶标记的细胞角蛋白85抗体 Alias Hair keratin K2.12; Hard keratin type II 5; Hb 5; HB5; hHb5; KRT85_HUMAN; K85; Keratin 85; keratin hair basic 5; Keratin type II cuticular Hb5; KRTHB5; Type II hair keratin Hb5; Type II keratin Kb25. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Rat, Dog, Cow, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 56kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human KRT85 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008]
Function:
KRT85 is a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity.
Subcellular Location:
Intermediate filament, Keratin filament
Similarity:
Belongs to the intermediate filament family.
Database links:Entrez Gene: 3891 Human
Omim: 602767 Human
SwissProt: P78386 Human
Unigene: 182507 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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