Product Name	Anti-GPR7/HRP
Chinese Name	辣根过氧化物酶标记的G protein-coupled receptor7抗体
Alias	GPCR GPR7; G protein coupled receptor 7; g protein coupled receptor gpr7; GPR7; MGC129755; Neuropeptides B and W receptor 1; Neuropeptides B/W receptor 1; Neuropeptides B/W receptor type 1; NPB and NPW receptor 1; NPBWR1; opioid somatostatin like receptor 7.
Research Area	Cell biology  Neurobiology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	59kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPR7
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other. They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB). In response to NPW and NPB, they play a role in the regulation of feeding behavior. GPR7 deficient mice develop an adult-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet. The genes encoding human GPR7 and GPR8 map to chromosomes 10q11.2-q21.1 and 10q13.3, respectively. Function: GPR7 interacts specifically with a number of opioid ligands. It is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals, and has a higher affinity for neuropeptide B. It has been reported in brain, mainly cerebellum and frontal cortex, and in the pituitary (O'Dowd et al., 1995). The mouse ortholog of GPR7 was shown by in situ hybridization to be expressed in discrete nuclei of brain, namely suprachiasmatic, arcuate, and ventromedial nuclei of hypothalamus. Subcellular Location: Cell membrane; Multipass membrane protein. Database links: Entrez Gene: 428544 Chicken Entrez Gene: 539470 Cow Entrez Gene: 101130191 Gorilla Entrez Gene: 100066961 Horse Entrez Gene: 10936 Human Entrez Gene: 237716 Mouse Entrez Gene: 100517153 Pig Entrez Gene: 100347723 Rabbit Entrez Gene: 498434 Rat Omim: 606704 Human SwissProt: O95800 Human SwissProt: Q6X632 Mouse Unigene: 40763 Human Unigene: 338361 Mouse Unigene: 484157 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Cartpieces

• 
• 1

  1Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 8

  8Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 5

  5Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• G

  GDelete

• 
• G

  GDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 5

  5Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout