Product Name	Anti-FARP1/HRP
Chinese Name	辣根过氧化物酶标记的软骨细胞Ezrin样蛋白抗体
Alias	CDEP; Chondrocyte derived ezrin like protein; FERM RhoGEF and pleckstrin domain containing protein 1; FERM RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived). PLEKHC2; FARP1_HUMAN.
Research Area	Cell biology  Neurobiology  Cell type markers  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	119kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FARP1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: FARP1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1), also known as PLEKHC2 or CDEP, is a 1,045 amino acid protein that contains one FERM domain, one DH domain and two PH domains. Existing as multiple alternatively spliced isoforms that are expressed in fetal heart, brain and spleen, as well as in adult lung, kidney and testis, FARP1 is thought to function as a Rho-guanine nucleotide exchange factor that may play a role in linking the cell membrane to the cytoskeleton. The gene encoding FARP1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. Function: The FARP1 protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain, and is believed to be a member of the band 4.1 superfamily, whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for the FARP1 gene, which shows increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. Subcellular Location: Cytoplasmic. Similarity: Contains 1 DH (DBL-homology) domain. Contains 1 FERM domain. Contains 2 PH domains. Database links: UniProtKB/Swiss-Prot: Q9Y4F1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Cartpieces

• 
• 1

  1Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 7

  7Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 5

  5Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• C

  CDelete

• 
• C

  CDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 5

  5Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout