Product Name	Anti-Epiphycan/HRP
Chinese Name	辣根过氧化物酶标记的硫酸软骨素蛋白多糖3抗体
Alias	Dermatan sulfate proteoglycan 3; DSPG3; Epiphycan; epiphycan proteoglycan; EPYC; EPYC_HUMAN; Pg Lb; PG-Lb; PGLB; Proteoglycan-Lb; SLRR3B; Small chondroitin/dermatan sulfate proteoglycan.
Research Area	Developmental biology  Stem cells  glycoprotein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
Applications	ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	35kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Epiphycan/DSPG3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: DSPG3 is a 322 amino acid secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family. Expressed in cartilage, ligament and placenta, DSPG3 may have a role in bone formation and in establishing the ordered structure of cartilage through matrix organization. It has been suggested that DSPG3 regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization. Subcellular Location: Secreted; extracellular space; extracellular matrix. Tissue Specificity: Cartilage, ligament, and placenta. Post-translational modifications: The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. Database links: Entrez Gene: 1833 Human Entrez Gene: 13516 Mouse Entrez Gene: 314772 Rat SwissProt: Q99645 Human SwissProt: P70186 Mouse Unigene: 435680 Human Unigene: 148886 Mouse Unigene: 159219 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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