Product Name	Anti-ACCN4/HRP
Chinese Name	辣根过氧化物酶标记的脑钠Channel protein4抗体
Alias	Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary.
Research Area	Neurobiology  Channel protein  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications	ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ACCN4/ASIC4
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]. Function: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Subunit: Homotrimer or heterotrimer with other ASIC proteins. Subcellular Location: .Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. Similarity: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily. Database links: Entrez Gene: 55515 Human Entrez Gene: 241118 Mouse Entrez Gene: 63882 Rat Omim: 606715 Human SwissProt: Q96FT7 Human SwissProt: Q7TNS7 Mouse SwissProt: Q9JHS6 Rat Unigene: 87469 Human Unigene: 110790 Mouse Unigene: 44831 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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