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Rabbit Anti-GABRG1/HRP Conjugated antibody
Rabbit Anti-GABRG1/HRP Conjugated antibody
GABA A Receptor gamma 1; GABA(A) receptor subunit gamma 1; GabaA/BZ; GABRG 1; GABRG1; Gamma aminobutyric acid (GABA A) receptor subunit gamma 1; Gamma aminobutyric acid A receptor, gamma 1; GBRG1;
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  • NO.:SL12078R-HRP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC
    concentration:1mg/ml
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Product Name Anti-GABRG1/HRP
Chinese Name 辣根过氧化物酶标记的G氨基丁酸受体γ1/GABAA Rγ1抗体
Alias GABA A Receptor gamma 1; GABA(A) receptor subunit gamma 1; GabaA/BZ; GABRG 1; GABRG1; Gamma aminobutyric acid (GABA A) receptor subunit gamma 1; Gamma aminobutyric acid A receptor, gamma 1; GBRG1;   
Research Area Neurobiology  The cell membrane受体  G protein-coupled receptor  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 50kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GABRG1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4. [provided by RefSeq, Jul 2008]

Function:
GABA A Receptor gamma 1 belongs to the ligand gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel.

Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi pass membrane protein.

Post-translational modifications:
May be palmitoylated

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG1 sub-subfamily.

Database links:

Entrez Gene: 2565 Human

Entrez Gene: 14405 Mouse

Entrez Gene: 140674 Rat

Omim: 137166 Human

SwissProt: Q8N1C3 Human

SwissProt: Q9R0Y8 Mouse

SwissProt: P23574 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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