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Product Name Anti-GABRG1/HRP Chinese Name 辣根过氧化物酶标记的G氨基丁酸受体γ1/GABAA Rγ1抗体 Alias GABA A Receptor gamma 1; GABA(A) receptor subunit gamma 1; GabaA/BZ; GABRG 1; GABRG1; Gamma aminobutyric acid (GABA A) receptor subunit gamma 1; Gamma aminobutyric acid A receptor, gamma 1; GBRG1; Research Area Neurobiology The cell membrane受体 G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 50kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GABRG1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4. [provided by RefSeq, Jul 2008]
Function:
GABA A Receptor gamma 1 belongs to the ligand gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel.
Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi pass membrane protein.
Post-translational modifications:
May be palmitoylated
Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG1 sub-subfamily.
Database links:Entrez Gene: 2565 Human
Entrez Gene: 14405 Mouse
Omim: 137166 Human
SwissProt: Q8N1C3 Human
SwissProt: Q9R0Y8 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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