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Rabbit Anti-TRAP1/HSP75/HRP Conjugated antibody
Rabbit Anti-TRAP1/HSP75/HRP Conjugated antibody
TRAP1; TRAP-1; Heat shock protein 75; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; TNF receptor associated protein 1; TNFR associated protein 1; TRAP 1; Tumor necrosis factor receptor associated protein; Tumor necrosis factor t
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  • NO.:SL1446R-HRP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Horse,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F
    concentration:1mg/ml
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Product Name Anti-TRAP1/HSP75/HRP
Chinese Name 辣根过氧化物酶标记的热休克蛋白75抗体
Alias TRAP1; TRAP-1; Heat shock protein 75; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; TNF receptor associated protein 1; TNFR associated protein 1; TRAP 1; Tumor necrosis factor receptor associated protein; Tumor necrosis factor type 1 receptor associated protein; TRAP1_HUMAN.  
Research Area Tumour  Cell biology  immunology  Signal transduction  Apoptosis  transcriptional regulatory factor  Mitochondrion  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 74kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HSP75
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Function:
Chaperone that expresses an ATPase activity.

Subunit:
Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.

Similarity:
Belongs to the heat shock protein 90 family.

Database links:

Entrez Gene: 10131 Human

Entrez Gene: 68015 Mouse

Entrez Gene: 287069 Rat

Entrez Gene: 416666 Chicken

Entrez Gene: 514472 Cow

Omim: 606219 Human

SwissProt: Q2TBI4 Cow

SwissProt: Q12931 Human

SwissProt: Q9CQN1 Mouse

SwissProt: Q5XHZ0 Rat

Unigene: 30345 Human

Unigene: 123366 Mouse

Unigene: 144695 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

信号传导(Signaling Intermediates)
HSP75/TRAP-1与TNF受体发生相互作用,可产生促进TNF的Signal transduction。

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