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Product Name Anti-LAIR-2/HRP Chinese Name 辣根过氧化物酶标记的白细胞相关免疫球蛋白样受体2抗体 Alias Leukocyte-associated immunoglobulin-like receptor 2; CD306; CD 306; CD-306; CD306 antigen; LAIR 2; Leukocyte associated Ig like receptor 2; Leukocyte associated immunoglobulin like receptor 2Leukocyte-associated immunoglobulin-like receptor 2; LAIR-2; LAIR2_HUMAN. Research Area immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 14kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LAIR-2/CD306 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
LAIR2 is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. LAIR2 contains one Ig-like C2-type (immunoglobulin-like) domain. There are two named isoforms.
Subcellular Location:
Secreted.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 3904 Human
Omim: 602993 Human
SwissProt: Q6ISS4 Human
Unigene: 43803 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
LAIR2、LAIR1都属于细胞黏附分子中免疫球蛋白超家族(IgSF)成员,是一种免疫细胞抑制性受体,定位于T细胞、B细胞、NK细胞及树状突等细胞中。
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