Product Name	Anti-MSS1/HRP
Chinese Name	辣根过氧化物酶标记的26S蛋白酶调节亚型7抗体
Alias	26S protease complex; mammalian suppressor of sgv-1 of yeast; MSS1; Nbla10058; protease 26S subunit 7; proteasome 26S ATPase subunit 2; Proteasome 26S subunit ATPase 2; proteasome 26S subunit ATPase 2; Protein MSS1; PSMC2; putative protein product of Nbla10058; S7 antibody; PRS7_HUMAN.
Research Area	Tumour  Cell biology  immunology  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Horse, )
Applications	WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	48kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MSS1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes and the endoplasmic reticulum. Function: he 26S protease is involved in the ATP-dependentdegradation of ubiquitinated proteins. The regulatory (or ATPase)complex confers ATP dependency and substrate specificity to the 26Scomplex. In case of HIV-1 infection, positive modulator ofTat-mediated transactivation. Subunit: Interacts with NDC80 and SQSTM1. Interacts with PAAF1.Interacts with HIV-1 Tat. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the AAA ATPase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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