Product Name	Anti-PNMA3/Gold
Chinese Name	胶体金标记的类Tumour性抗原MA3抗体
Alias	MA3; MA5; MGC132756; MGC132758; Paraneoplastic antigen Ma3; Paraneoplastic cancer testis brain antigen; Paraneoplastic Ma antigen 3; PNMA 3; PNMA3; PNMA3_MOUSE.
Research Area	Tumour  Cell biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Rat, )
Applications	IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	52kDa
Form	Lyophilized or Liquid
Concentration	0.4mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse PNMA3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
Storage	Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
Product Detail	background: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Subcellular Location: Nucleus > nucleolus. Tissue Specificity: Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney. Similarity: Belongs to the PNMA family. Contains 1 CCHC-type zinc finger. Database links: Entrez Gene: 29944 Human Entrez Gene: 245468 Mouse GenBank: NP_037496 Human Omim: 300675 Human SwissProt: Q9UL41 Human SwissProt: Q8JZW8 Mouse Unigene: 449627 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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