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Rabbit Anti-DHX33/Gold Conjugated antibody
Rabbit Anti-DHX33/Gold Conjugated antibody
DDX33; DHX33_HUMAN; DEAD box polypeptide 33; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 33; DEAH (Asp Glu Ala His) box polypeptide 33; DEAH box protein 33; FLJ21972.
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Details

Product Name Anti-DHX33/Gold
Chinese Name 胶体金标记的DHX33蛋白抗体
Alias DDX33; DHX33_HUMAN; DEAD box polypeptide 33; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 33; DEAH (Asp Glu Ala His) box polypeptide 33; DEAH box protein 33; FLJ21972.  
Research Area Cell biology  Developmental biology  Apoptosis  Cell differentiation  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Chicken, Dog, Cow, Horse, )
Applications IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 79kDa
Form Lyophilized or Liquid
Concentration 0.4mg/ml
immunogen KLH conjugated synthetic peptide derived from human DHX33
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
Storage Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
Product Detail background:
This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Function:
DHX33 is a DEAD box protein whose function has not yet been determined. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.

Subunit:
Interacts with UBTF.

Subcellular Location:
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Predominantly in the nucleolus. During mitosis, localizes with the nucleolar organizing regions.

Similarity:
Belongs to the DEAD box helicase family. DEAH subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

Database links:

Entrez Gene: 56919 Human

SwissProt: Q9H6R0 Human

Unigene: 250456 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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