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Product Name Anti-COX7A1/Gold Chinese Name 胶体金标记的细胞色素C氧化酶蛋白7A1抗体 Alias COX7A; COX7A1; COX7AH; COX7AM; CX7A1_HUMAN; Cytochrome c oxidase subunit 7A1; Cytochrome c oxidase subunit 7A1 mitochondrial; Cytochrome c oxidase subunit VIIa H; Cytochrome c oxidase subunit VIIa heart; Cytochrome c oxidase subunit VIIa heart/muscle isoform; Cytochrome c oxidase subunit VIIa M; Cytochrome c oxidase subunit VIIa muscle; Cytochrome c oxidase subunit VIIa polypeptide 1 (muscle); Cytochrome c oxidase subunit VIIa polypeptide 1; Cytochrome c oxidase subunit VIIa-H; Cytochrome c oxidase subunit VIIa-heart; Cytochrome c oxidase subunit VIIa-M; Cytochrome c oxidase subunit VIIa-muscle; mitochondrial. Research Area Tumour Cell biology Signal transduction Cell type markers The new supersedes the old Mitochondrion Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 6.7kDa Form Lyophilized or Liquid Concentration 0.4mg/ml immunogen KLH conjugated synthetic peptide derived from human COX7A1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Storage Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles. Product Detail background:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes. [provided by RefSeq, Jul 2008]
Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Location:
Mitochondrion inner membrane.
Tissue Specificity:
Belongs to the cytochrome c oxidase VIIa family.
Similarity:
Belongs to the cytochrome c oxidase VIIa family.
Database links:Entrez Gene: 1346 Human
Omim: 123995 Human
SwissProt: P24310 Human
Unigene: 421621 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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