Product Name	Anti-Hrasls3/Gold
Chinese Name	胶体金标记的HRAS样抑制因子3抗体
Alias	H rev 107 protein homolog; HRAS like suppressor 3; HREV107 3; HREV107; Renal carcinoma antigen NY REN 65; Adipose specific phospholipase A2; Group XVI phospholipase A2; HREV107; HRSL3_MOUSE; AdPLA; HRSL3; HRASLS3; HREV107-1; HREV107-3; H-REV107-1.
Research Area	immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	18kDa
Form	Lyophilized or Liquid
Concentration	0.4mg/ml
immunogen	KLH conjugated synthetic peptide derived from the middle of mouse Hrasls3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
Storage	Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
Product Detail	background: HRASLS3 specifically catalyzes the release of fatty acids from phospholipids in adipose tissue and also has a weak lysophospholipase activity. It is a tumor suppressor that may be involved in interferon-dependent cell death. Function: Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N-and O-acylation activity is hardly detectable. Also has weak lysophospholipase activity. Subunit: Interacts with PPP2R1A; this interaction might decrease PP2A activity. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm, perinuclear region. Tissue Specificity: Ubiquitously expressed in normal tissues but down-regulated in primary carcinomas or in many cell lines derived from tumors. Highly expressed in white adipose tissue and in adipocytes. Expressed at lower levels in brown adipose tissue. Similarity: Belongs to the H-rev107 family. Database links: Entrez Gene: 11145 Human Entrez Gene: 225845 Mouse Omim: 613867 Human SwissProt: P53816 Human SwissProt: Q8R3U1 Mouse Unigene: 502775 Human Unigene: 274810 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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