Product Name	Anti-GPR136/FITC
Chinese Name	FITC标记的G protein-coupled receptor136抗体
Alias	G protein-coupled receptor 136; G-protein coupled receptor PGR12; Gpr136; HGNC:21318; Neuropsin; OPN5; Opsin 5; PGR12; TMEM13; Transmembrane protein 13; OPN5_HUMAN; GPCR GPR136.
Research Area	Neurobiology  Signal transduction  The cell membrane受体  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	40kDa
Cellular localization	The cell membrane
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human G protein-coupled receptor 136
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: GPCR GPR136, also known as Opsin 5, is a member of the guanine nucleotide binding protein (G protein) coupled receptor superfamily. This gene belongs to the seven exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven exon opsin genes, this gene may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants encoding different isoforms. ESTs for the GPR136 gene have been identified from human normal testis and B cell/lung/testis libraries.. Subcellular Location: Membrane; Multipass membrane protein. Tissue Specificity: Detected in brain and retina and cell lines derived from neural retina. Post-translational modifications: It is uncertain whether Cys-315 or Cys-316 is palmitoylated. Similarity: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. Database links: Entrez Gene: 221391 Human Entrez Gene: 353344 Mouse Entrez Gene: 316259 Rat SwissProt: Q6U736 Human SwissProt: Q6VZZ7 Mouse SwissProt: Q7TQN6 Rat Unigene: 213717 Human Unigene: 184937 Mouse Unigene: 97222 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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