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Rabbit Anti-HIV gp41/FITC Conjugated antibody
Rabbit Anti-HIV gp41/FITC Conjugated antibody
HIV1 gp41; HIV-1 gp41; HIV1gp41; HIVgp41; Transmembrane protein gp41; Glycoprotein 41; Human Immunodeficiency Virus 1; HIV1 ENV (gp160); HIV1 gp160; HIV1gp160; HIV-1 gp160; env; Env polyprotein; Envelope glycoprotein gp160; Glycoprotein 41; gp41; HIV1; HI
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Product Name Anti-HIV gp41/FITC
Chinese Name FITC标记的艾滋病病毒抗体
Alias HIV1 gp41; HIV-1 gp41; HIV1gp41; HIVgp41; Transmembrane protein gp41; Glycoprotein 41; Human Immunodeficiency Virus 1; HIV1 ENV (gp160); HIV1 gp160; HIV1gp160; HIV-1 gp160; env; Env polyprotein; Envelope glycoprotein gp160; Glycoprotein 41; gp41; HIV1; HIV1 clade a; HIV1/Clade A; SU; Surface protein; Human Immunodeficiency Virus Type 1 TM; Transmembrane protein; ENV_HV1MV.   
Research Area Bacteria and viruses  
Immunogen Species Rabbit
Clonality Polyclonal
React Species
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 39/93kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from Transmembrane protein gp41
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


人类免疫缺陷病毒Ⅰ型(HIV-1)的包膜glycoproteingp120、gp41
HIV感染后可刺激机体生产囊膜蛋白(Gp120,Gp41)抗体
病毒呈球形,直径100~120nm,电镜下可见一致密的圆锥状核心,内含病毒RNA分子和酶(逆转录酶、整合酶、蛋白酶),病毒外层囊膜系双层脂质蛋白膜,其中嵌有gp120和gp41,分别组成刺突和Transmembrane protein。

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