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Product Name Anti-defensin beta 2/FITC Chinese Name FITC标记的防御素β2/Defensin β2抗体 Alias beta-defensin 2 precursor; beta Defensin 2; beta-defensin 2; Defb2; DFB4A_HUMAN. Research Area Microbiology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Rat, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 8kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from rat beta 2 Defensin Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in the skin and respiratory tract.
Similarity:
Belongs to the beta-defensin family. LAP/TAP subfamily.
Database links:
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
防御素在人体中广泛分布的,目前已知的α-防御素有6种,研究人员从人体的肾脏、气管、鼻粘膜与唾液中也发现了两种β防御素,在许多器官的epithelial cells与非上皮组织的细胞中发现了β-防御素。
Defensin β2在维持肌体天然免疫功能、介导炎症反应以及调节特异性免疫中的作用引起人们的重视,防御素的表达与病原体的入侵紧密相关。
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