Product Name	Anti-ID2/FITC
Chinese Name	FITC标记的DNA结合抑制因子2抗体
Alias	ID2; GIG-8; GIG8; GIG 8; Helix loop helix protein ID2; ID2A; ID-2; ID2H; Inhibitor of differentiation 2; Inhibitor of DNA binding 2; Inhibitor of DNA binding 2, dominant negative helix loop helix protein; MGC26389; bHLHb26; Cell growth inhibiting gene 8; DNA binding protein inhibitor ID 2; BHLHB26; ID2_HUMAN.
Research Area	Tumour  immunology  Chromatin and nuclear signals  Signal transduction  Apoptosis  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	15kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GIG8/ID2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, and may play a role in negatively regulating cell differentiation. Members of the ID family are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. They inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner, by suppressing their heterodimerization partners through the HLH domains. Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression. Subunit: Heterodimer with other HLH proteins. Interacts with GATA4, IFI204 and NKX2-5. Interacts with NR0B2. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Highly expressed in early fetal tissues, including those of the central nervous system. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Database links: Entrez Gene: 3398 Human Entrez Gene: 15902 Mouse Omim: 600386 Human SwissProt: Q02363 Human SwissProt: P41136 Mouse Unigene: 180919 Human Unigene: 34871 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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