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Product Name Anti-NDUFS3/FITC Chinese Name FITC标记的Mitochondrion复合物NDUFS3蛋白抗体 Alias CI 30KD; Complex I 30KD; NADH-Ubiquinone Oxidoreductase Fe-S Protein 3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit. Research Area Tumour Cell biology immunology Neurobiology Mitochondrion Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 30kDa Cellular localization The cell membrane Mitochondrion Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NDUFS3 (181-230aa) Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The multisubunit NADH:ubiquinone oxidoreductase is the first enzyme complex in the electron transport chain of mitochondria. By use of chaotropic agents, complex I can be fragmented into 3 different fractions: a flavoprotein fraction, an iron-sulfur protein (IP) fraction, and a hydrophobic protein (HP) fraction. The IP fraction contains NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, and NDUFA5.
Subunit:
Mammalian complex I is composed of 45 different subunits. Interacts with NDUFAF3.
Subcellular Location:
Mitochondrion inner membrane.
Similarity:
Belongs to the complex I 30 kDa subunit family.
Database links:Entrez Gene: 4722 Human
Entrez Gene: 68349 Mouse
Omim: 603846 Human
SwissProt: O75489 Human
SwissProt: Q9DCT2 Mouse
Unigene: 502528 Human
Unigene: 30113 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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