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Rabbit Anti-PCDHA2/FITC Conjugated antibody
Rabbit Anti-PCDHA2/FITC Conjugated antibody
KIAA0345 like 12; PCDH alpha 2; PCDH ALPHA2; Protocadherin alpha 2; PCDA2_HUMAN.
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  • NO.:SL11116R-FITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Details

Product Name Anti-PCDHA2/FITC
Chinese Name FITC标记的原钙粘附蛋白α2抗体
Alias KIAA0345 like 12; PCDH alpha 2; PCDH ALPHA2; Protocadherin alpha 2; PCDA2_HUMAN.  
Research Area Neurobiology  Signal transduction  Cell adhesion molecule  Cytoskeleton  Extracellular matrix  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 100kDa
Cellular localization The cell membrane 
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PCDHA2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA2 (protocadherin alpha 2) is a 948 amino acid single-pass type I membrane protein that contains six cadherin domains and functions as a potential calcium-dependent cell-adhesion protein, possibly playing a role in the creation and maintenance of neuronal connections. Mltiple isoforms of PCDHA2 exist due to alternative splicing events.

Function:
Contains 6 cadherin domains and three named isoforms. Potential calcium dependent cell adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single pass type I membrane protein

Similarity:
Contains 6 cadherin domains.

Database links:
UniProtKB/Swiss-Prot: Q9Y5H9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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