Product Name	Anti-Phospho-JunB (Thr102 + Thr104)/FITC
Chinese Name	FITC标记的磷酸化活化蛋白激酶B抗体
Alias	Phospho-JunB (Thr102/Thr104); P-JunB (Phospho Thr102/Thr104); Activator protein 1; AP 1; AP1; Jun B; Jun B proto oncogene; Jun B protooncogene; JunB proto oncogene; JunB protoncogene 9; JunB protooncogene; Transcription factor jun B; Transcription factor junB; JUNB_HUMAN; Transcription factor jun-B; Transcription factor junB.
Product Type	Phosphorylated anti
Research Area	Tumour  transcriptional regulatory factor  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Guinea Pig, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	38kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated Synthesised phosphopeptide derived from human JunB around the phosphorylation site of Thr102/Thr104 [TT(p-T)P(p-T)PP]
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'. Function: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Subunit: Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). Subcellular Location: Nucleus. Post-translational modifications: Ubiquitinated by ITCH, leading to its degradation. Similarity: Belongs to the bZIP family. Jun subfamily. Contains 1 bZIP (basic-leucine zipper) domain. Database links: Entrez Gene: 3726 Human Entrez Gene: 16477 Mouse Entrez Gene: 24517 Rat Omim: 165161 Human SwissProt: P17275 Human SwissProt: P09450 Mouse SwissProt: P24898 Rat Unigene: 25292 Human Unigene: 1167 Mouse Unigene: 470093 Mouse Unigene: 15806 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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