TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-PERP/p53 apoptosis effector related to PMP22/Cy7 Chinese Name Cy7标记的p53凋亡相关作用蛋白PMP22抗体 Alias KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP22; P53 induced protein PIGPC1; P53-induced protein PIGPC1; Perp; PERP TP53 apoptosis effector; PERP_HUMAN; PIGPC 1; PIGPC1; THW antibody TP53 apoptosis effector; Transmembrane protein THW. Research Area Cell biology Signal transduction Apoptosis Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 21kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human p53 apoptosis effector related to PMP22 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.
Subcellular Location:
Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes.
Tissue Specificity:
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.
Similarity:
Belongs to the TMEM47 family.
Database links:Entrez Gene: 64065 Human
Entrez Gene: 64058 Mouse
Omim: 609301 Human
SwissProt: Q96FX8 Human
SwissProt: Q9JK95 Mouse
Unigene: 201446 Human
Unigene: 28209 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode
Scan Whatsapp Qrcode