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Rabbit Anti-PERP/p53 apoptosis effector related to PMP22/Cy7 Conjugated antibody
Rabbit Anti-PERP/p53 apoptosis effector related to PMP22/Cy7 Conjugated antibody
KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector rel
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  • NO.:SL10783R-Cy7
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,)
    concentration:1mg/ml
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Product Name Anti-PERP/p53 apoptosis effector related to PMP22/Cy7
Chinese Name Cy7标记的p53凋亡相关作用蛋白PMP22抗体
Alias KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP22; P53 induced protein PIGPC1; P53-induced protein PIGPC1; Perp; PERP TP53 apoptosis effector; PERP_HUMAN; PIGPC 1; PIGPC1; THW antibody TP53 apoptosis effector; Transmembrane protein THW.  
Research Area Cell biology  Signal transduction  Apoptosis  Cytoskeleton  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 21kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human p53 apoptosis effector related to PMP22
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.

Subcellular Location:
Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes.

Tissue Specificity:
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.

Similarity:
Belongs to the TMEM47 family.

Database links:

Entrez Gene: 64065 Human

Entrez Gene: 64058 Mouse

Omim: 609301 Human

SwissProt: Q96FX8 Human

SwissProt: Q9JK95 Mouse

Unigene: 201446 Human

Unigene: 28209 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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