Product Name	Anti-MYO3A/Cy7
Chinese Name	Cy7标记的肌球蛋白3A抗体
Alias	deafness, autosomal recessive 30; DFNB30; Myo3a; MYO3A_HUMAN; Myosin IIIA; Myosin-IIIa.
Research Area	Cell biology  immunology  Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	186kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MYO3A
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008] Function: Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing. Subcellular Location: Cytoplasm, cytoskeleton. Tissue Specificity: Strongest expression in retina, retinal pigment epithelial cells, cochlea and pancreas. DISEASE: Deafness, autosomal recessive, 30 Similarity: In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. Contains 3 IQ domains. Contains 1 myosin head-like domain. Contains 1 protein kinase domain. Database links: Entrez Gene: 53904 Human Omim: 606808 Human SwissProt: Q8NEV4 Human Unigene: 662630 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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