Product Name	Anti-Neurotrypsin/Cy7
Chinese Name	Cy7标记的神经胰蛋白酶抗体
Alias	BSSP 3; BSSP3; Leydin; MGC12722; MOTOPSIN; MRT1; NETR_HUMAN; Neurotrypsin; protease, serine, 12 (neurotrypsin, motopsin); Prss12; Serine protease 12.
Research Area	Cell biology  Neurobiology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	95kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Neurotrypsin
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010] Function: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Subcellular Location: Secreted. Tissue Specificity: Brain and Leydig cells of the testis. DISEASE: Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1) [MIM:249500]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Similarity: Belongs to the peptidase S1 family. Contains 1 kringle domain. Contains 1 peptidase S1 domain. Contains 4 SRCR domains. Database links:  Entrez Gene: 8492 Human Entrez Gene: 19142 Mouse Entrez Gene: 85266 Rat SwissProt: P56730 Human SwissProt: O08762 Mouse SwissProt: Q99JC8 Rat Unigene: 445857 Human Unigene: 9431 Mouse Unigene: 86653 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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