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Rabbit Anti-phospho-IL13 receptor alpha 1 (Tyr405)/Cy7 Conjugated antibody
Rabbit Anti-phospho-IL13 receptor alpha 1 (Tyr405)/Cy7 Conjugated antibody
IL13 receptor alpha 1 (phospho Y405); p-IL13 receptor alpha 1 (phospho Y405);bB128O4.2.1 (interleukin 13 receptor, alpha 1); Cancer/testis antigen 19; CD213A1; CD213A1 Antigen; CT 19; CT19; I13R1_HUMAN; IL 13 receptor subunit alpha 1; IL 13R alpha 1; IL 1
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  • NO.:SL18135R-Cy7
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Pig,Horse,Rabbit,)
    concentration:1mg/ml
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Product Name Anti-phospho-IL13 receptor alpha 1 (Tyr405)/Cy7
Chinese Name Cy7标记的磷酸化白细胞介素13受体α1抗体
Alias IL13 receptor alpha 1 (phospho Y405); p-IL13 receptor alpha 1 (phospho Y405); bB128O4.2.1 (interleukin 13 receptor, alpha 1); Cancer/testis antigen 19; CD213A1; CD213A1 Antigen; CT 19; CT19; I13R1_HUMAN; IL 13 receptor subunit alpha 1; IL 13R alpha 1; IL 13R subunit alpha 1; IL 13Ra; IL 13RA1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; IL13 receptor alpha 1 chain; IL13R; IL13RA; IL13RA1; Interleukin 13 receptor alpha 1; Interleukin 13 receptor alpha 1 chain; interleukin 13 receptor subunit alpha 1; Interleukin-13 receptor subunit alpha-1; NR 4; NR4.   
Product Type Phosphorylated anti 
Research Area Cell biology  Signal transduction  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Pig, Horse, Rabbit, )
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 42kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human phospho-IL13 receptor alpha 1 (Tyr405)
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

Function:
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.

Similarity:
Belongs to the type I cytokine receptor family. Type 5 subfamily.

Database links:

Entrez Gene: 3597 Human

Entrez Gene: 16164 Mouse

Omim: 300119 Human

SwissProt: P78552 Human

SwissProt: O09030 Mouse

Unigene: 496646 Human

Unigene: 24208 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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