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Rabbit Anti-SPERT/Cy7 Conjugated antibody
Rabbit Anti-SPERT/Cy7 Conjugated antibody
CBY2; Chibby homolog 2; FLJ35810; Novel leucine zipper testicular protein; NURIT; Protein chibby homolog 2; Spermatid associated; Spermatid associated protein; Spermatid flower like structure protein; Testis specific leucine zipper protein nurit.
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Details

Product Name Anti-SPERT/Cy7
Chinese Name Cy7标记的精子细胞相关蛋白抗体
Alias CBY2; Chibby homolog 2; FLJ35810; Novel leucine zipper testicular protein; NURIT; Protein chibby homolog 2; Spermatid associated; Spermatid associated protein; Spermatid flower like structure protein; Testis specific leucine zipper protein nurit.  
Research Area Cell biology  Developmental biology  Transporter  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Rat,  (predicted: Mouse, Cow, Horse, Rabbit, Sheep, )
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 52kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SPERT
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
A variety of morphological and molecular changes are required for spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPERT (spermatid associated), also known as CBY2 (chibby homolog 2), spermatid flower-like structure protein or NURIT, is a 448 amino acid novel leucine-zipper protein belonging to the chibby family of proteins.Expressed uniquely in the spermatid flower-like structure, SPERT interacts with Nek1, a member of the NIMA-family kinase family that is associated centrosomal stability and ciliogenesis. Containing a leucine-zipper motif and two coiled-coil regions, SPERT is transcribed through the elongation stage of the spermatids. SPERT is absent from mature spermatozoa and is thought to be involved in transporting proteins that are to be discarded via the residual bodies.

Function:
Spermatid-associated protein (SPERT) belongs to the chibby family, SPERT subfamily. It exists as a homodimer and binds to NEK1. There are two named isoforms produced by alternative splicing.

Subcellular Location:
Cytoplasmic membrane bounded vesicle.

Similarity:
Belongs to the chibby family. SPERT subfamily.

Database links:

Entrez Gene: 220082 Human

SwissProt: Q8NA61 Human

Unigene: 186363 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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