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Product Name Anti-OSCP/Cy7 Chinese Name Cy7标记的ATP合酶亚基O抗体 Alias ATP synthase O subunit mitochondrial precursor; ATP synthase subunit O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; ATP5O; ATPO; ATPO_HUMAN; mitochondrial; Mitochondrial ATP synthase, O subunit; Oligomycin sensitivity conferral protein; OSCP. Research Area Cell biology Signal transduction Cell type markers The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Dog, Pig, Cow, Rabbit, Sheep, Monkey, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 21kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OSCP Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. [provided by RefSeq, Jul 2008]
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Subcellular Location:
Mitochondrion. Mitochondrion inner membrane.
Similarity:
Belongs to the ATPase delta chain family.
Database links:Entrez Gene: 539 Human
Entrez Gene: 698480 Monkey
Entrez Gene: 100328815 Rabbit
Omim: 600828 Human
SwissProt: P48047 Human
Unigene: 409140 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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