TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-SFRS3/Cy7 Chinese Name Cy7标记的丝氨酸/苏氨酸SRp20抗体 Alias arginine/serine-rich 3; Pre mRNA splicing factor SRP20; Pre-mRNA-splicing factor SRP20; Serine/arginine-rich splicing factor 3; Splicing factor; Splicing factor arginine/serine rich 20 kD; Splicing factor arginine/serine rich 3; SRp20; SRSF3; SRSF3_HUMAN; X16. Research Area Cell biology Signal transduction Kinases and Phosphatases Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish, Sheep, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 19kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SFRS3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010]
Function:
May be involved in RNA processing in relation with cellular proliferation and/or maturation.
Subcellular Location:
Nucleus.
Post-translational modifications:
Extensively phosphorylated on serine residues in the RS domain.
Similarity:
Belongs to the splicing factor SR family.
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 6428 Human
Entrez Gene: 20383 Mouse
Entrez Gene: 368925 Zebrafish
Omim: 603364 Human
SwissProt: P84103 Human
SwissProt: P84104 Mouse
SwissProt: Q9D6W4 Mouse
SwissProt: Q801U3 Zebrafish
Unigene: 405144 Human
Unigene: 6787 Mouse
Unigene: 3509 Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode