Product Name	Anti-TRK fused gene/Cy7
Chinese Name	Cy7标记的TRK融合基因蛋白抗体
Alias	TRK-T3; TRK fused gene; FLJ36137; HMSNP; OTTHUMP00000214045; OTTHUMP00000214046; OTTHUMP00000214047; OTTHUMP00000214048; Protein TFG; SPG57; TF6; TFG; TFG_HUMAN; TRK fused; TRK fused gene; TRK fused gene protein; TRK-fused gene protein; TRKT3; TRKT3 oncogene.
Research Area	Tumour  Cell biology  Signal transduction  Apoptosis  lymphocyte  b-lymphocyte  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	43kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TRK fused gene
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010] Tissue Specificity: Ubiquitous. DISEASE: Defects in TFG are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TFG is found in thyroid papillary carcinomas. Translocation t(1;3)(q21;q11) with NTRK1. The TFG sequence is fused to the 3'-end of NTRK1 generating the TRKT3 (TRK-T3) fusion transcript. Database links: Entrez Gene: 10342 Human Entrez Gene: 21787 Mouse Entrez Gene: 360709 Rat Omim: 602498 Human SwissProt: Q92734 Human Unigene: 518123 Human Unigene: 425970 Mouse Unigene: 24822 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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