Product Name	Anti-KCNK2/Cy7
Chinese Name	Cy7标记的钾离子Channel protein2抗体
Alias	hTREK 1c; hTREK 1e; K2p2.1; K2P2.1 potassium channel; KCNK 2; Kcnk2; KCNK2_HUMAN; MGC126742; MGC126744; Outward rectifying potassium channel protein TREK 1; Outward rectifying potassium channel protein TREK-1; Outward rectifying potassium channel protein TREK1; Potassium channel subfamily K member 2; Potassium inwardly rectifying channel subfamily K member 2; Tandem pore domain potassium channel TREK 1; Tandem pore domain potassium channel TREK1; TPKC1; TREK 1; TREK 1 K(+) channel subunit; TREK; TREK-1 K(+) channel subunit; TREK1; TWIK related potassium channel 1; Two pore domain potassium channel TREK 1; Two pore domain potassium channel TREK-1; Two pore domain potassium channel TREK1; Two pore potassium channel 1; Two pore potassium channel TPKC1.
Research Area	Cell biology  Neurobiology  Channel protein  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	47kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human KCNK2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Outward rectifying potassium channel. Subunit: Homodimer (Potential). Subcellular Location: Membrane. Tissue Specificity: Isoform 4 is detected in kidney, adrenal gland and brain where it is preferentially expressed in the amygdala but not found in thalamus, hypothalamus, hippocampus or substantia nigra. Post-translational modifications: Phosphorylation at Ser-348 controls the reversible conversion from a leak channel to a voltage-dependent channel. Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. Database links: Entrez Gene: 3776 Human Entrez Gene: 16526 Mouse Entrez Gene: 170899 Rat Omim: 603219 Human SwissProt: O95069 Human SwissProt: P97438 Mouse Unigene: 497745 Human Unigene: 33304 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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