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Rabbit Anti-CR16/Cy7 Conjugated antibody
Rabbit Anti-CR16/Cy7 Conjugated antibody
Corticosteroids and regional expression protein 16 homolog; WAS/WASL-interacting protein family member 3; Wipf3; WIPF3_HUMAN.
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Details

Product Name Anti-CR16/Cy7
Chinese Name Cy7标记的糖皮质激素区域表达蛋白16抗体
Alias Corticosteroids and regional expression protein 16 homolog; WAS/WASL-interacting protein family member 3; Wipf3; WIPF3_HUMAN.  
Research Area Cell biology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Horse, )
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 49kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CR16
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
CR16 is a 483 amino acid proline-rich cytoplasmic protein that is thought to regulate cytoskeletal organization. A member of both the verprolin and Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) families, CR16 colocalizes with N-WASP (Neuronal Wiskott-Aldrich syndrome protein) in tips of growth cone filopodia, primary hippocampal neurons and Sertoli cell-spermatid junctions. CR16 and N-WASP functionally interact to influence spermatogenesis. CR16 is predominantly expressed in brain and testis, contains one WH2 domain, a KLKR motif, three profilin-binding motifs and is encoded by a gene that maps to human chromosome 7p15.1.

Function:
May be a regulator of cytoskeletal organization. May have a role in spermatogenesis.

Subcellular Location:
Cytoplasm. In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone.

Similarity:
Belongs to the verprolin family.
Contains 1 WH2 domain.

Database links:

Entrez Gene: 644150 Human

SwissProt: A6NGB9 Human

Unigene: 709280 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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