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Product Name Anti-PL6/Cy7 Chinese Name Cy7标记的胎盘蛋白6抗体 Alias TMEM115; transmembrane protein 115; PP6; Placental protein 6; TM115_HUMAN. Research Area Cell biology Signal transduction Epigenetics Transmembrane protein The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 38kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PL6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Transmembrane proteins contain transmembrane domains that are usually characterized by alpha-helical structures. Transmembrane proteins exist as thermodynamically stable hetero- and homodimers that interact with the lipid bilayer and are involved in both material exchange and communication between the cell and the environment. PL6 is a 351 amino acid multi-pass membrane protein that is highly expressed in kidney and skeletal muscle with lower levels of expression detected in liver, placenta, prancreas, lung, heart and brain. PL6 contains one phosphoserine residue and several transmembrane domains, suggesting that it may participate in protein exchange and signaling events between cells.
Function:
PL6 is an integral membrane protein with signal transduction activity.
Subcellular Location:
Membrane; Multi-pass membrane protein
Database links:Entrez Gene: 11070 Human
Entrez Gene: 56395 Mouse
NCBI: 5902022 Human
SwissProt: Q12893 Human
SwissProt: Q9WUH1 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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