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Product Name Anti-ACN9/Cy7 Chinese Name Cy7标记的ACN9蛋白抗体 Alias ACN 9; acn9; ACN9 homolog (S. cerevisiae); ACN9 homolog; SDHF3_HUMAN; DC11; Protein ACN9 homolog mitochondrial; Protein ACN9 homolog, mitochondrial; Succinate Dehydrogenase Complex Assembly Factor 3; SDH Assembly Factor 3; DC11; Sdh7; Research Area Cell biology Signal transduction transcriptional regulatory factor Channel protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 11kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ACN9 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
SDHAF3 (Succinate Dehydrogenase Complex Assembly Factor 3) is a Protein Coding gene. Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Subcellular Location:
Mitochondrion matrix
Similarity:
Belongs to the ACN9 family.
Belongs to the complex I LYR family. SDHAF3 subfamily.
Database links:Entrez Gene: 57001 Human
Entrez Gene: 71238 Mouse
SwissProt: Q9NRP4 Human
SwissProt: Q8BQU3 Mouse
Unigene: 592269 Human
Unigene: 389086 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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