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Product Name Anti-IL17D/Cy7 Chinese Name Cy7标记的白介素-17D抗体 Alias Interleukin-17D; IL 17D; IL 27; IL17D; IL-17D; IL27; Interleukin 17D; Interleukin 27; Interleukin-17; pfam06083; IL17D_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, Rat, (predicted: Cow, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 20kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-17D Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
Function:
Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed preferentially in adipose, skeletal muscle and CNS.
Similarity:
Belongs to the IL-17 family.
Database links:Entrez Gene: 53342 Human
Entrez Gene: 239114 Mouse
Omim: 607587 Human
SwissProt: Q8TAD2 Human
Unigene: 655142 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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