TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-GM-CSF/Cy7 Chinese Name Cy7标记的粒细胞-巨噬细胞克隆刺激因子抗体 Alias Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN. Research Area Tumour immunology Signal transduction Chemokine Cell Surface Molecule Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 14kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GM-CSF (102-111aa) Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008].
Function:
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Subunit:
Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
Subcellular Location:
Secreted.
Similarity:
Belongs to the GM-CSF family.
Database links:Entrez Gene: 1437 Human
Omim: 138960 Human
SwissProt: P04141 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GM-CSF是vascular endothelial cell、单核细胞和成纤维细胞合成的glycoprotein。能促进中性粒细胞成熟;刺激成熟的粒细胞从骨髓释出;增强中性粒细胞趋化及吞噬功能。
Scan Wechat Qrcode
Scan Whatsapp Qrcode