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Product Name Anti-PPIL1/Cy7 Chinese Name Cy7标记的亲环素相关蛋白1抗体 Alias CGI 124; CGI-124; CGI124; Cyclophilin related gene 1; cyclophilin-related gene 1; cyclophilinrelated gene 1; CYPL1; hCyPX; MGC678; peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase-like 1; Peptidylprolyl isomerase (cyclophilin) like 1; peptidylprolyl isomerase (cyclophilin)-like 1; peptidylprolyl isomerase (cyclophilin)like 1; peptidylprolyl isomerase (cyclophilin)like1; peptidylprolyl isomerase like 1; PPIase; PPIL1; PPIL1_HUMAN; rotamase; Rotamase PPIL1. Research Area Cell biology immunology Chromatin and nuclear signals Signal transduction Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 18kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PPIL1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Peptidyl-prolyl cis-trans isomerase (PPIL1) is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.
Subunit:
Identified in the spliceosome C complex. Interacts with SNW1.
Tissue Specificity:
Ubiquitous, with the most abundant expression in heart and skeletal muscle.
Similarity:
Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.
Contains 1 PPIase cyclophilin-type domain.
Database links:
UniProtKB/Swiss-Prot: Q9Y3C6.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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