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Product Name Anti-EPB41L1/Cy5 Chinese Name Cy5标记的EPB41L1蛋白抗体 Alias 4.1N; Band 4.1 like protein 1; Band 4.1-like protein 1; DKFZp686H17242; E41L1_HUMAN; EPB41L 1; Epb41l1; Erythrocyte membrane protein band 4.1 like 1; KIAA0338; MGC11072; MRD11; Neuron type nonerythroid protein 4.1; Neuronal protein 4.1; Nonerythroid protein 4.1; Nonerythroid protein 4.1, neuron type; OTTHUMP00000030825; OTTHUMP00000030826; OTTHUMP00000030827; OTTHUMP00000030829. Research Area Cell biology Signal transduction Binding protein Cell type markers Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Rhesus monkey) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 88kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human EPB41L1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Function:
May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.
Subcellular Location:
Cytoplasm; cytoskeleton.
Tissue Specificity:
Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.
Similarity:
Contains 1 FERM domain.
Database links:Entrez Gene: 2036 Human
Entrez Gene: 13821 Mouse
Omim: 602879 Human
SwissProt: Q9H4G0 Human
SwissProt: Q9Z2H5 Mouse
Unigene: 722186 Human
Unigene: 20852 Mouse
Unigene: 20361 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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