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Product Name Anti-Synaptotagmin-2/Cy5 Chinese Name Cy5标记的突触Binding protein相关基因2抗体 Alias Synaptotagmin 2; Synaptotagmin II; Synaptotagmin2; SynaptotagminII; SYT 2; Syt II; SytII.Synaptotagmin II; SYNII; Syt2; RATSYNII; SYNII; FLJ42519; KIAA4194; LOC100127887; mKIAA4194; R74640; RATSYNII; SYNAPTOTAGMIN 2; SYT2; SytII; SYT2_HUMAN. Research Area Cell biology Neurobiology Binding protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 46kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human synaptotagmin-2 C-terminus Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM]
Subunit:
Homotetramer. Interacts with stonin 2. Interacts with SCAMP5.
Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein.
Similarity:
Belongs to the synaptotagmin family.
Contains 2 C2 domains.
Database links:Entrez Gene: 127833 Human
Entrez Gene: 20980 Mouse
Omim: 600104 Human
SwissProt: Q8N9I0 Human
SwissProt: P46097 Mouse
Unigene: 25422 Human
Unigene: 5102 Mouse
Unigene: 88574 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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