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Rabbit Anti-ATP4B/Cy5 Conjugated antibody
Rabbit Anti-ATP4B/Cy5 Conjugated antibody
Gastric H(+)/K(+) ATPase subunit beta; H+K+ ATPase; ATP4B; ATP6B; ATPase H+/K+ exchanging beta polypeptide; ATPase H+/K+ transporting beta polypeptide;Gastric H K ATPase catalytic subunit; Gastric H+/K+ ATPase beta subunit; Gastric hydrogen potassium ATPa
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Details

Product Name Anti-ATP4B/Cy5
Chinese Name Cy5标记的氢钾ATP酶Channel protein抗体
Alias Gastric H(+)/K(+) ATPase subunit beta; H+K+ ATPase; ATP4B; ATP6B; ATPase H+/K+ exchanging beta polypeptide; ATPase H+/K+ transporting beta polypeptide;Gastric H K ATPase catalytic subunit; Gastric H+/K+ ATPase beta subunit; Gastric hydrogen potassium ATPase; Gastric hydrogen potassium ATPase beta; Hydrogen/potassium exchanging ATPase 4B; Potassium transporting ATPase beta chain; Potassium transporting ATPase subunit beta; Proton pump; Proton pump beta chain; ATP4B_HUMAN.  
Research Area Cell biology  immunology  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 33kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ATP4B
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]

Function:
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.

Subunit:
Composed of two subunits: alpha (catalytic) and beta.

Subcellular Location:
Cell membrane

Tissue Specificity:
Expressed at highest levels in heart, skeletal

Similarity:
Belongs to the X(+)/potassium ATPases subunit beta family.

Database links:

Entrez Gene: 496 Human

Entrez Gene: 11945 Mouse

Entrez Gene: 397131 Pig

Entrez Gene: 24217 Rat

Omim: 137217 Human

SwissProt: P51164 Human

SwissProt: P50992 Mouse

SwissProt: P18434 Pig

SwissProt: P18597 Rabbit

SwissProt: P18598 Rat

Unigene: 434202 Human

Unigene: 154039 Mouse

Unigene: 10033 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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