Product Name	Anti-phospho-Ephrin B (Tyr324 + Tyr329)/Cy5
Chinese Name	Cy5标记的磷酸化Ephrin B抗体
Alias	Ephrin B (phospho Y324); p-Ephrin B (phospho Y324); Ephrin B (phospho Y329); p-Ephrin B (phospho Y329); phospho-Ephrin B1(Tyr324+Tyr329); phospho-Ephrin B2 (Tyr311+Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN.
Product Type	Phosphorylated anti
Research Area	Tumour  Cell biology  immunology  Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	36kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated Synthesised phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr324/329
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. Subunit: Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein. Subcellular Location: Membrane; single pass type I membrane protein. Tissue Specificity: Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments. Similarity: Belongs to the ephrin family. Contains 1 ephrin RBD (ephrin receptor-binding) domain. Database links: Entrez Gene: 1947 Human Entrez Gene: 1948 Human Entrez Gene: 13641 Mouse Entrez Gene: 13642 Mouse Entrez Gene: 25186 Rat Omim: 300035 Human Omim: 600527 Human SwissProt: P52799 Human SwissProt: P98172 Human SwissProt: P52795 Mouse SwissProt: P52800 Mouse SwissProt: P52796 Rat SwissProt: Q6P7B6 Rat Unigene: 144700 Human Unigene: 149239 Human Unigene: 44398 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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